immune-modulation
Immune-modulation in plants refers to the enhancement or modification of a plant's natural defense mechanisms to strengthen resistance against pathogens and environmental stresses. By understanding and leveraging immune-modulation, researchers can develop crop varieties that are more resilient to disease while requiring fewer chemical pesticide inputs. This approach offers a sustainable avenue for addressing disease pressures and environmental challenges that threaten agricultural productivity and food security.
open_in_new WikipediaPubMed · 2026-03-21
Scientists are developing tiny particles extracted from plants that can treat ulcerative colitis, a chronic gut inflammation. These plant-based nanoparticles are safe, naturally biocompatible, and work by reducing inflammation and restoring healthy gut bacteria.
Isolation uses centrifugation methods (ultracentrifugation, differential/density gradient centrifugation) to extract plant-derived exosome-like nanovesicles
PDELNs reduce colitis through three mechanisms: potent anti-inflammatory effects, gut microbiota remodeling, and immune response regulation via plant microRNAs and metabolites
PDELNs demonstrate excellent safety profile with zero reported toxicity, making them viable for clinical translation