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Association between dietary intakes and gut microbiota composition in individuals with Lynch syndrome: a cross-sectional analysis of the AAS-Lynch study.

PubMed · 2026-05-28

In people with a hereditary cancer syndrome, eating more plant proteins and fewer animal products was linked to greater diversity of beneficial gut bacteria, while Western-style diets high in red meat and saturated fat were linked to reduced microbial diversity.

1

Higher plant protein intake and a greater ratio of plant-to-animal protein were positively associated with gut microbiota alpha-diversity (Shannon and Simpson indices) in 95 Lynch syndrome patients.

2

Western dietary patterns, red meat, saturated fatty acids, cholesterol, and animal proteins were all negatively associated with gut microbial diversity.

3

Plant protein intake was specifically linked to higher relative abundance of Lachnospiraceae_NK3A20_group, a bacterial family associated with gut health.

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