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systemic-immunity

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Identification and characterization of an NHP-biosynthetic pathway in defense and systemic acquired resistance in common bread wheat

OpenAlex · 2027-01-01

Researchers identified and characterized the biochemical pathway wheat uses to produce N-hydroxypipecolic acid (NHP), a small molecule that acts as a master immune signal, priming the entire plant for defense after a local infection. This extends a discovery previously made only in lab plants to one of the world's most important food crops.

1

The NHP biosynthetic pathway — previously characterized mainly in the model plant Arabidopsis — was identified and functionally characterized in common bread wheat (Triticum aestivum).

2

NHP production in wheat is linked to activation of systemic acquired resistance (SAR), suggesting the pathway is conserved and functional across distantly related plant species.

3

This work provides a molecular basis for engineering or selecting wheat varieties with enhanced whole-plant immune priming, a trait with direct implications for reducing fungicide dependency in cereal production.

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