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Identification and characterization of an NHP-biosynthetic pathway in defense and systemic acquired resistance in common bread wheat

Plant Signaling

Wheat fields that can mount a whole-plant immune response after a single infected stem could need far fewer fungicide applications — meaning cleaner grain and less chemical runoff into the streams near farms you know.

When a plant gets infected in one spot, it can send chemical alarm signals through its whole body so every leaf and stem becomes harder to infect — this is called systemic acquired resistance. Scientists have now found the specific chemical assembly line in bread wheat that makes the key alarm molecule. Understanding this in wheat is a big step toward breeding varieties that fight disease from the inside, reducing the need for sprays.

Key Findings

1

The NHP biosynthetic pathway — previously characterized mainly in the model plant Arabidopsis — was identified and functionally characterized in common bread wheat (Triticum aestivum).

2

NHP production in wheat is linked to activation of systemic acquired resistance (SAR), suggesting the pathway is conserved and functional across distantly related plant species.

3

This work provides a molecular basis for engineering or selecting wheat varieties with enhanced whole-plant immune priming, a trait with direct implications for reducing fungicide dependency in cereal production.

chevron_right Technical Summary

Researchers identified and characterized the biochemical pathway wheat uses to produce N-hydroxypipecolic acid (NHP), a small molecule that acts as a master immune signal, priming the entire plant for defense after a local infection. This extends a discovery previously made only in lab plants to one of the world's most important food crops.

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Abstract Preview

The full abstract for this thesis is available in the body of the thesis, and will be available when the embargo expires.

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hub This connects to 11 other discoveries — Wheat, Bread Wheat plant-signaling, crop-improvement, disease-resistance +1 more 5 related articles

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Wheat is a group of wild and domesticated grasses of the genus Triticum. As cereals, they are cultivated for their grains, which are staple foods around the world. Well-known wheat species and hybrids include the most widely grown common wheat, spelt, durum, emmer, einkorn, and Khorasan or Kamut....