nanovesicles
Nanovesicles are tiny membrane-enclosed particles, typically 30–200 nanometers in diameter, that cells release to shuttle proteins, nucleic acids, and signaling molecules between cells and organisms. In plant science, they play key roles in intercellular communication, stress responses, and host-pathogen interactions—including how plants defend against or are manipulated by invading fungi, bacteria, and viruses. Researchers are also exploring engineered plant-derived nanovesicles as sustainable delivery systems for agrochemicals and RNA-based crop protection strategies.
open_in_new WikipediaPubMed · 2026-05-02
Tiny vesicles naturally produced by plants carry bioactive molecules that can enter the human body and influence disease. This review synthesizes current research showing these plant-derived nanovesicles could become a new class of low-toxicity drug delivery vehicles and treatments for cancer, inflammation, and liver and brain disorders.
Plant-derived nanovesicles (PDNVs) demonstrate low immunogenicity and high biocompatibility, making them safer candidates for drug delivery than many synthetic nanoparticles.
PDNVs have shown therapeutic potential across a broad range of conditions including cancer, inflammation, viral infections, liver disorders, brain disorders, osteoporosis, and tissue regeneration.
PDNVs can be isolated from a wide variety of plant sources, and the review documents their full lifecycle from biogenesis and purification through routes of administration and biodistribution in vivo.