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Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans.
PubMed · 2026-04-22
Scientists identified a gene called Dsx1 that controls whether crustaceans (small shrimp-like animals) develop male or female physical traits. When they disabled this gene using CRISPR, male crustaceans grew female-shaped legs — confirming Dsx1 as a master switch for sex-specific body features.
1
Dsx1 shows male-biased expression throughout leg development in male amphipod crustaceans (Morinoia aosen)
2
RNA interference knockdown of Dsx1 caused feminization of regenerated male legs, directly linking the gene to sexually dimorphic traits
3
CRISPR-Cas9 knockout in a crustacean model species (Parhyale hawaiensis) confirmed feminization of male legs, validating conserved Dsx1 function across species