Researchers built BioTD, the world's largest open database of biotoxins — poisons made by animals, plants, and microbes — giving drug developers free access to data on nearly 9,000 toxins and their biological effects. This fills a major gap in drug discovery, since many life-saving medicines trace back to natural venoms and plant toxins.
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BioTD contains 14,607 data records covering 8,975 toxins from over 900 species, sourced from 5,220 references and patents.
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The database includes 8,185 biological activity records categorized into five groups: Activity, Safety, Kinetics, Hemolysis, and other physiological indicators.
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BioTD also documents 1,532 toxin mutants and annotates structural details like disulfide bonds and signal peptide sequences — all freely downloadable.
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