PubMed · 2026-06-02
Researchers built BioTD, the world's largest open database of biotoxins — poisons made by animals, plants, and microbes — giving drug developers free access to data on nearly 9,000 toxins and their biological effects. This fills a major gap in drug discovery, since many life-saving medicines trace back to natural venoms and plant toxins.
BioTD contains 14,607 data records covering 8,975 toxins from over 900 species, sourced from 5,220 references and patents.
The database includes 8,185 biological activity records categorized into five groups: Activity, Safety, Kinetics, Hemolysis, and other physiological indicators.
BioTD also documents 1,532 toxin mutants and annotates structural details like disulfide bonds and signal peptide sequences — all freely downloadable.