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Sustainable biotechnology applies genetic, molecular, and cellular tools to develop crops and agricultural systems that reduce environmental impact while maintaining or improving productivity. In plant science, it encompasses engineering stress tolerance, improving nutrient use efficiency, and reducing dependence on synthetic inputs like pesticides and fertilizers. These advances are critical for addressing food security and climate resilience without compromising ecosystem health.

Multigram-scale stereoselective synthesis of neurosteroid isomers by gut microbial isolates using plant biomass-derived medium.

PubMed · 2026-04-02

Scientists used gut bacteria fed on sugarcane and soybean byproducts to manufacture brain-active medicines at scale, cutting production costs by 90% and carbon emissions by 95% compared to conventional lab media — all without any animal-derived ingredients.

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Three gut bacterial strains each produced a different neurosteroid isomer with high stereospecificity, eliminating the need for costly chiral separation steps.

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Using a plant-derived medium made from sugarcane molasses and enzymatically treated okara (soybean pulp), researchers achieved over 95% conversion of progesterone into target neurosteroids.

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Compared to standard lab growth media, the plant-based medium reduced production costs by 90% and carbon footprint by 95% in multigram-scale batch trials.