Plant-derived nanomedicine involves the synthesis and application of nanoparticles using plant extracts and phytochemicals as reducing or capping agents, creating biocompatible nanostructures with medicinal properties. This field bridges plant biochemistry and nanotechnology, highlighting the functional diversity of plant secondary metabolites and their capacity to stabilize nanoparticles for use in drug delivery, antimicrobial treatments, and therapeutic applications. For plant scientists, it underscores the value of understanding phytochemical composition and opens new avenues for leveraging plant biodiversity in the development of sustainable, green-synthesized nanomaterials.
Researchers engineered a wearable patch that uses nanoparticles derived from medicinal plants to deliver a chemotherapy drug and genetic regulators directly to aggressive breast cancer tumors, improving targeting precision while reducing toxic side effects.
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Plant-derived exosomes acted as biocompatible carriers, enabling cascade tumor targeting that concentrated the drug payload at the tumor site rather than throughout the body
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Combining plant exosomes, miRNA gene regulators, and cisplatin chemotherapy produced a synergistic anti-tumor effect greater than any single agent alone
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The microneedle wearable platform demonstrated high safety in models of triple-negative breast cancer, a subtype that currently has very limited targeted treatment options
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