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Improving menstrual and vaginal health for all (IMVAHA): protocol for a randomised cross-over trial assessing the impact of menstrual products on the vaginal microbiome of women aged 18-35 years in Cameroon, Peru and Switzerland.
PubMed · 2026-04-22
This clinical trial protocol describes a study testing how different menstrual products (pads, tampons, menstrual cups) affect the vaginal microbiome of women across Cameroon, Peru, and Switzerland — with no connection to plant science.
1
300 women (100 per country) will be enrolled in a crossover trial across Cameroon, Peru, and Switzerland
2
Each participant uses pads, tampons, and menstrual cups for 2 menstrual cycles each, with vaginal swabs analyzed via 16S rRNA sequencing
3
Primary outcome is microbiome composition ratio; secondary outcomes include pH, toxic shock syndrome bacteria screening, and participant-reported symptoms