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Root-attacking soil worms may be beaten by microbes, gene editing and RNA sprays

PubMed · 2026-09-24

Microscopic soil worms that attack plant roots cost growers billions, and the old chemical fixes are disappearing. This review argues that healthier soil microbes, gene editing, RNA-based sprays, and faster approval of low-risk biological products can replace them.

1

Biological control products have strong safety records and scalable production, but regulatory and market hurdles slow their adoption.

2

Suppressive microbial consortia, validated delivery systems, and diagnostics can shift soils toward durable nematode suppression.

3

RNA interference target discovery for perennial crops, paired with transgrafting, and affordable RNA-based biopesticides offer new nematode control options, while genome editing that mirrors natural allelic variation could warrant streamlined oversight.

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