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Reduced confidence intervals and novel candidate genes for quantitative trait loci associated with apple scab resistance in Malus domestica

bioRxiv · 2026-04-10

Scientists identified and narrowed down four genetic regions in apple trees that help them resist apple scab, a destructive fungal disease, and found the specific genes likely responsible — opening the door to breeding disease-resistant apples without heavy pesticide use.

1

Four of five candidate resistance regions (QTLs) were validated in a population of 1,970 apple trees, with one region (qF3) failing to confirm

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43 newly developed genetic markers substantially narrowed the location of each resistance region, making them far more useful for breeding programs

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Candidate genes identified include receptor-like proteins and RNAi-related genes, suggesting apple trees use multiple, complementary defense strategies against the fungus