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flavonoid-biosynthesis

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Genome sequence of the medicinal plant Urtica dioica reveals the genetic basis of the flavonoid metabolism

bioRxiv · 2026-05-16

Scientists sequenced the full genome of stinging nettle, revealing the genes responsible for producing flavonoids and anthocyanins — the compounds behind the plant's medicinal properties and its reddening response to stress.

1

The assembled stinging nettle genome spans 1.1 billion base pairs with a high-quality N50 scaffold length of 40.7 Mbp, indicating a highly continuous assembly.

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Genes responsible for flavonoid and anthocyanin biosynthesis were identified, linking them to the plant's visible stress response — reddening of leaves under high light or nitrogen deprivation.

3

RNA sequencing data was combined with cross-species gene hints to produce a comprehensive protein-coding gene annotation, enabling future study of medically relevant compounds.

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