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One nonprofit's plasmid library fueled global CRISPR gene-editing boom
PubMed · 2026-07-23
A nonprofit lab supply hub called Addgene has shipped CRISPR gene-editing tools over 300,000 times worldwide, with growing use in plants, yeast, and other organisms beyond the usual medical research, showing how a single sharing system helped genome editing spread globally.
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Over 20,000 CRISPR-related plasmids have been deposited by more than 1,000 labs and distributed over 300,000 times globally.
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Guide RNA and HDR template plasmids make up the bulk of deposits, while cloning backbones are the most requested items.
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Editing tools now span multiple effectors (Cas9, Cas12) and modalities (base editing, prime editing, epigenetic editing, CRISPRi/a) across mammalian, bacterial, plant, yeast, and insect research.