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Copper-flavonoid combo fights colon cancer cells in lab tests

Medicinal Plants

The flavonoids behind this compound are the same antioxidant-rich pigments found in everyday plants like onions, apples, and citrus peels, and they're getting fresh attention for medicinal potential beyond the garden.

Flavonoids are natural pigments plants make to protect themselves from stress and pests, and they're found in tons of common fruits, vegetables, and herbs. Researchers paired one of these plant compounds with copper to build a new molecule, then tested it against colorectal cancer cells in the lab. The combo triggered cell death in the cancer cells and also seemed to stop them from taking on the traits that let cancer spread through the body.

Key Findings

1

A copper(II)-flavonoid complex induced apoptosis (programmed cell death) in colorectal cancer cells.

2

The same complex suppressed epithelial-mesenchymal transition (EMT), a process cancer cells use to become mobile and invasive.

3

Both effects occurred concomitantly, suggesting the compound works through a dual anti-cancer mechanism.

chevron_right Technical Summary

Scientists combined copper with a plant-derived flavonoid to create a compound that killed colorectal cancer cells in lab tests and blocked the process cancer cells use to spread to other organs.

hub This connects to 8 other discoveries — Flavonoid-containing plants medicinal-plants, ethnobotany 5 related articles

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