Jackfruit leaves show real promise as a stomach ulcer treatment
Medicinal Plants
The jackfruit tree in a backyard orchard or fruit market isn't just prized for its sweet flesh; its leaves may hold real medicinal value for gut health.
Researchers fed rats aspirin to give them stomach ulcers, then treated some with an extract made from jackfruit leaves. The highest dose of leaf extract worked almost as well as a standard ulcer medication at healing the damaged stomach lining, shrinking the ulcers dramatically compared to untreated rats.
Key Findings
300 mg/kg dose of jackfruit leaf ethanol extract produced the best anti-ulcer effect, with an ulcer index of 2.00
Therapeutic percentage at the top dose reached 84.41%, approaching the effect of the omeprazole positive control
Results followed a clear dose-response pattern across 100, 200, and 300 mg/kg groups, tested in 18 male rats using Kruskal-Wallis and Mann-Whitney analysis
chevron_right Technical Summary
Jackfruit leaf extract protected rats from aspirin-induced stomach ulcers, with the highest dose working nearly as well as a common ulcer drug.
Abstract Preview
Original paper
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) SEBAGAI ANTIULCER BERDASARKAN PARAMETER INDEKS ULKUS PADA TIKUS JANTAN (Rattus norvegicus) YANG DIINDUKSI ASPIRIN
Peptic ulcer disease is a disorder of the upper gastrointestinal tract caused by an imbalance between aggressive and defensive factors of the gastric mucosa. This condition can be treated using Pro...
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