PubMed · 2026-06-30
Researchers reviewed how tiny engineered particles called nanomaterials can dramatically improve healing of chronic wounds that resist standard treatments. By delivering drugs precisely, fighting infection, and reducing inflammation, these materials outperform traditional dressings, and the field is moving toward personalized, sensor-guided wound care.
Nanomaterials categorized by shape (0D nanoparticles, 1D nanofibers, 2D graphene oxide composites) each offer distinct advantages including large surface area, tunable drug release, and multifunctional antibacterial and anti-inflammatory action.
Plant-derived nanomaterials are gaining attention for their antioxidant properties and potential for scalable, environmentally sustainable production compared to synthetic alternatives.
Animal studies and small clinical trials show nanomaterial-based dressings can accelerate wound closure versus traditional methods, though efficacy varies by wound type and model.