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Enhanced stability and reusability of metagenomic laccase via immobilization on functionalized mesoporous silica for antibiotic contaminant removal.

PubMed · 2026-03-26

Researchers engineered a reusable enzyme system that breaks down antibiotic pollution in water. By attaching a soil-microbe-derived enzyme to specialized silica particles, they achieved over 75% removal of doxycycline and sustained performance across 10 reuse cycles — a meaningful step toward practical, low-cost water cleanup.

1

The immobilized enzyme removed 76.7% of doxycycline and 53.7% of tetracycline from water within 24 hours.

2

After 10 consecutive reuse cycles, the system retained over 83% of its doxycycline-degrading activity and 73% for tetracycline.

3

Enzyme leaching was very low (9.6% at room temperature), making the system practical for repeated real-world use.