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Systemic defense refers to the plant-wide activation of immune responses triggered by localized infection or wounding, allowing the entire organism to mount resistance against future attacks. This whole-plant signaling phenomenon—mediated by mobile molecules such as salicylic acid, jasmonic acid, and volatile compounds—is critical to understanding how plants survive in pathogen-rich environments without an adaptive immune system. Research into systemic defense mechanisms has broad implications for developing disease-resistant crops and reducing reliance on chemical pesticides.

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Systemic defense signaling in Austrian pine.

PubMed · 2026-05-01

Austrian pine trees mount a sophisticated, whole-tree defense against a deadly fungal pathogen by coordinating multiple plant hormones in a precise sequence. Early abscisic acid signaling triggers the alarm, while sustained jasmonic acid and its mobile form carry the defensive message throughout the tree.

1

Early abscisic acid (ABA) signaling is the first hormone wave after infection, initiating the systemic defense response in Austrian pine against Diplodia pinea

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Sustained jasmonic acid (JA) signaling — confirmed by both hormone measurements and gene expression data — is required for full activation of whole-tree induced resistance

3

Mobile methyl jasmonate (MeJA) serves as a long-distance defense signal, with its spatiotemporal accumulation pattern matching genes involved in systemic signal propagation and defense