PubMed · 2026-05-19
Scientists have uncovered how a single master gene called LEC2 acts like a reset button in plant cells, switching ordinary leaf or root cells back into embryo-forming cells capable of growing a whole new plant. Understanding this molecular switch could help researchers propagate difficult crops and engineer plants more efficiently.
LEC2 acts as a dual-function regulator: it both responds to the plant hormone auxin and directly rewires how DNA is packaged (epigenetic remodeling), making it a central hub for plant cell reprogramming.
LEC2 recruits chromatin-remodeling proteins to switch on embryo-development genes in non-embryonic (somatic) cells, revealing a mechanistic link between hormone signaling and gene accessibility.
LEC2-based strategies offer a conceptual framework for improving regeneration efficiency across crop species, with direct implications for clonal propagation and genetic transformation pipelines.
