iNaturalist:
Sugar maple spotting slows as Canada's fall color fades
iNaturalist:
Red oak spotting slows down as fall colors fade
iNaturalist:
This fuzzy forest moss is suddenly everywhere in Canada
iNaturalist:
Milkweed sightings stay high across Canada as autumn sets in
iNaturalist:
Invasive buckthorn sightings surge across Canada this week
iNaturalist:
Pokeweed sightings dip slightly as fall observation seaso...
iNaturalist:
This weedy wetland plant is everywhere on iNaturalist this week
iNaturalist:
Eastern redcedar is having a moment on iNaturalist this week
iNaturalist:
Sugar maple spotting slows as Canada's fall color fades
iNaturalist:
Red oak spotting slows down as fall colors fade
iNaturalist:
This fuzzy forest moss is suddenly everywhere in Canada
iNaturalist:
Milkweed sightings stay high across Canada as autumn sets in
Expanding genetic regulatory and efflux mechanisms for improved polymyxin production in Paenibacillus polymyxa.
PubMed · 2026-03-29
Researchers engineered a soil bacterium that naturally protects plant roots to produce far more of an antibiotic compound called polymyxin, using cheap agricultural waste as feed stock. A single protein tweak boosted output by 25% even on low-cost sugarcane molasses and cellulose scraps.
1
A single amino acid swap (T38W) in the efflux transporter PmxD boosted polymyxin P production nearly fourfold over wild-type in lab conditions.
2
Deleting transporter genes pmxCD cut polymyxin P output by roughly 50%, confirming the transporter's role in secretion.
3
Using a low-cost medium of cellulose hydrolysate and sugarcane molasses, the engineered strain produced 87.66 mg/L vs. 70.31 mg/L in the control, a 24.68% titer improvement.
