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plant-nanotherapy

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Plant-nanotherapy is the application of nanotechnology—specifically nanoparticles and nanomaterials—to enhance plant health, growth, and stress tolerance. This field is significant for plant science because it offers the potential for more efficient and targeted delivery of nutrients, bioactive compounds, and treatments while reducing the quantity of chemicals required. Nanotherapeutic approaches also enable plants to better withstand environmental stresses and combat diseases, opening new avenues for improving crop yield and agricultural sustainability.

Biogenesis, preparation, characterization, therapeutic mechanisms and safety evaluation of plant-derived exosome-like nanovesicles in the treatment of ulcerative colitis.

PubMed · 2026-03-21

Scientists are developing tiny particles extracted from plants that can treat ulcerative colitis, a chronic gut inflammation. These plant-based nanoparticles are safe, naturally biocompatible, and work by reducing inflammation and restoring healthy gut bacteria.

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Isolation uses centrifugation methods (ultracentrifugation, differential/density gradient centrifugation) to extract plant-derived exosome-like nanovesicles

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PDELNs reduce colitis through three mechanisms: potent anti-inflammatory effects, gut microbiota remodeling, and immune response regulation via plant microRNAs and metabolites

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PDELNs demonstrate excellent safety profile with zero reported toxicity, making them viable for clinical translation