plant-metabolites
Plant metabolites are organic compounds produced through plant biochemical processes, including both essential molecules required for growth and energy, and specialized compounds that mediate plant defense and environmental adaptation. These metabolites are fundamental to plant science because they determine plant fitness, resilience, and interactions with their environment. Understanding plant metabolites is crucial for improving crop productivity, enhancing disease resistance, and discovering bioactive compounds with applications in medicine and agriculture.
PubMed · 2026-03-21
Scientists are developing tiny particles extracted from plants that can treat ulcerative colitis, a chronic gut inflammation. These plant-based nanoparticles are safe, naturally biocompatible, and work by reducing inflammation and restoring healthy gut bacteria.
Isolation uses centrifugation methods (ultracentrifugation, differential/density gradient centrifugation) to extract plant-derived exosome-like nanovesicles
PDELNs reduce colitis through three mechanisms: potent anti-inflammatory effects, gut microbiota remodeling, and immune response regulation via plant microRNAs and metabolites
PDELNs demonstrate excellent safety profile with zero reported toxicity, making them viable for clinical translation