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optogenetics

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The protein turnover and trafficking of Chlamyopsin6 is regulated by IFT88 and IFT52 in the Chlamydomonas reinhardtii.

PubMed · 2026-05-27

Scientists discovered how a light-sensitive protein in green algae gets shuttled to specific locations inside the cell — findings that could improve how researchers use light to control biological processes in living systems.

1

Chlamyopsin5 localizes primarily to the eyespot and its trafficking is independent of the IFT (intraflagellar transport) machinery

2

Chlamyopsin6 localizes to both the flagella and eyespot, and its delivery to the flagella requires the IFT transport system

3

IFT88 and IFT52 stabilize Chlamyopsin6 protein turnover, while IFT20 physically interacts with Chlamyopsin6

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