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Watermelon plants edited to survive common herbicide without added genes

PubMed · 2026-07-06

Scientists used a precise gene-editing tool to make watermelon naturally resistant to glyphosate herbicide, without introducing foreign DNA. The resulting plants tolerate real-world herbicide doses and can be used as breeding parents to pass this trait to new varieties.

1

Prime editing of the watermelon EPSPS gene conferred glyphosate resistance without inserting foreign DNA

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Heterozygous mutant plants tolerated field-level herbicide doses with no measurable growth penalty

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Visible markers in the editing platform allow breeders to identify and select edited plants for use as parental lines

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