human-genetics
Human genetics is the study of inheritance, variation, and genome function in humans, spanning classical genetics, genomics, and molecular biology. In plant science, insights and tools from human genetics—such as genome sequencing technologies, statistical methods for mapping traits, and gene-editing techniques—are often adapted to study plant heredity, evolution, and disease resistance. This cross-disciplinary exchange helps researchers understand shared genetic principles and develop improved crops through comparative genomic approaches.
open_in_new WikipediaPubMed · 2026-07-15
Scientists built a massive map of over 92 million connections between human DNA switches (enhancers) and the genes they control, using data from nearly 1,500 tissue and cell samples. This resource helps researchers pinpoint which genes are affected by disease-linked genetic variants.
Created a resource of over 92 million enhancer-gene interactions across 1,458 biosamples covering 369 cell types and tissues
Developed ENCODE-rE2G, a predictive model benchmarked against 10,356 CRISPR-tested element-gene pairs, 30,000+ eQTLs, and 569 GWAS variants
Identified promoter class and enhancer-enhancer synergy as key features guiding enhancer-promoter communication, beyond just activity and 3D contacts