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Unveiling the potential of banana (
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Conditional Expression of Cas9 and dCas9 in
PubMed · 2026-04-06
Scientists engineered blowflies—a major livestock pest—to change sex based on a common antibiotic, potentially allowing pest populations to be collapsed without chemicals.
1
CRISPR-based sex transformation was successfully triggered in the Australian sheep blowfly using tetracycline-repressible genetic switches
2
Both active Cas9 and catalytically inactive dCas9 constructs were tested, demonstrating flexible design options for genetic control systems
3
Conditional sex transformation offers a targeted, heritable mechanism to suppress pest populations as an alternative to broad-spectrum insecticides