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Viruses deliver gene-editing tools into wheat's complex genome

PubMed · 2026-03-10

Scientists are using plant viruses as delivery vehicles to carry gene-editing tools directly into crops, skipping the slow, costly lab transformation process that has long bottlenecked CRISPR's use in agriculture. A key recent milestone: heritable edits achieved in hexaploid wheat, one of the world's most important and genetically complex food crops.

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Virus-induced genome editing (VIGE) has advanced from proof-of-concept in model plants to practical application in agricultural crops.

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A recent breakthrough achieved heritable genome edits in hexaploid wheat, a crop with a highly complex genome that has resisted conventional CRISPR delivery methods.

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VIGE bypasses plant transformation and tissue culture, the two biggest bottlenecks limiting CRISPR's use across diverse crop genotypes.

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