A single protein in plant cells that senses the ripening hormone ethylene may also detect cell stress and let calcium flow into the cell. This suggests plants use one hub to coordinate growth, stress responses, and hormone signals.
1
Arabidopsis ETR1, a canonical ethylene receptor, also acts as a redox sensor at the endoplasmic reticulum, with disulfide-dependent dimerization controlling its conformation and activity.
2
Subfamily I ethylene receptors, including ETR1, function as Ca2+-permeable channels, directly linking ethylene perception to rapid rises in cytosolic calcium.
3
The review proposes ETR1 as a multifunctional hub integrating hormone, redox, and Ca2+ signaling, and flags unresolved questions about how these functions relate mechanistically.
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