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Phenolic acid biosynthesis is associated with deleterious microbiome changes during Plasmodiophora brassicae-induced clubroot in pakchoi.

PubMed · 2026-02-14

When a devastating soil pathogen infects cabbage-family vegetables, it hijacks the plant's own chemistry to wipe out the beneficial bacteria that would otherwise fight the disease — creating a vicious cycle that makes infection worse.

1

Beneficial bacteria from the Rhizobiaceae family were significantly more abundant in healthy plants than diseased ones, and one strain (Rhizobium sp. 25F3) showed strong disease-suppressing activity when added to soil.

2

Two specific phenolic acid compounds produced by infected plants were shown to both inhibit the growth of beneficial Rhizobiaceae bacteria and accelerate Plasmodiophora brassicae infection simultaneously.

3

Genes responsible for phenolic acid production were upregulated in diseased roots, confirming that the plant's own stress response inadvertently fuels the pathogen's success by dismantling its microbial defenses.