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miR2916-p5 and miR6478 from

PubMed · 2026-03-26

Tiny molecular messengers called microRNAs found in traditional Chinese medicinal herbs can survive digestion, enter human blood, and potentially influence how our genes work — suggesting that the plants we consume may communicate with our bodies at a molecular level.

1

Two specific plant microRNAs — miR2916-p5 and miR6478 — were identified in traditional Chinese medicinal herbs and are the focus of cross-kingdom regulatory study.

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Plant-derived microRNAs can survive mammalian gastrointestinal digestion, enter the bloodstream, and reach target tissues in the body.

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The composition, types, and functions of microRNAs in traditional Chinese medicinal herbs remain poorly characterized, representing a significant research gap.