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cellular-signaling

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Cellular signaling refers to the complex molecular communication networks that allow plant cells to detect, interpret, and respond to internal and external stimuli. In plants, these pathways regulate critical processes such as growth, development, stress responses, and adaptation to environmental changes like drought, temperature fluctuations, and pathogen attack. Understanding how plants transmit and integrate signals at the cellular level is fundamental to improving crop resilience and developing strategies for sustainable agriculture.

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Tongmai Yangxin pill mitigates myocardial ischemia/reperfusion injury by improving mitochondrial function and mitophagy: A potential role of estrogen receptor alpha and PTEN-induced putative kinase 1/Parkin pathway.

PubMed · 2026-04-06

A traditional Chinese herbal medicine called Tongmai Yangxin pill (TMYX) was found to protect heart tissue from damage caused by blocked-then-restored blood flow by improving how heart cells clean up and recycle damaged cellular components.

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148 distinct chemical compounds from the herbal formula were identified in blood and tissue samples after administration

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Silencing the estrogen receptor alpha (ERα) gene in heart cells completely abolished the protective effects of the herbal treatment, confirming it as a critical target

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TMYX reduced myocardial fibrosis and oxidative stress in rats with simulated heart attack injury by restoring mitochondrial recycling (mitophagy) balance via the PINK1/Parkin signaling pathway