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Boron compound stresses and kills skin cancer cells in lab dishes

OpenAlex · 2026-09-24

Boric acid, the same boron compound plants need in tiny amounts, damaged human melanoma cells in a lab dish by stressing them with reactive oxygen molecules and altering a key growth-signaling pathway. It's early cell-culture work, so it says nothing yet about treating cancer or about garden use.

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Boric acid reduced the viability of MALME-3M human melanoma cells in culture.

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Treatment was associated with oxidative stress, meaning a buildup of reactive oxygen molecules.

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Boric acid changed Wnt signaling, a pathway that regulates cell growth and division.

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