biocompatible-medicine
Biocompatible medicine encompasses therapeutic approaches and drug delivery systems designed to function effectively within plant physiology without causing adverse effects or rejection. This is significant for plant science because it enables the use of plants as biological platforms for pharmaceutical production, allowing researchers to engineer organisms that synthesize medicinal compounds. The field advances understanding of how living plant tissues can safely produce and maintain therapeutic molecules for medical applications.
PubMed · 2026-03-21
Scientists are developing tiny particles extracted from plants that can treat ulcerative colitis, a chronic gut inflammation. These plant-based nanoparticles are safe, naturally biocompatible, and work by reducing inflammation and restoring healthy gut bacteria.
Isolation uses centrifugation methods (ultracentrifugation, differential/density gradient centrifugation) to extract plant-derived exosome-like nanovesicles
PDELNs reduce colitis through three mechanisms: potent anti-inflammatory effects, gut microbiota remodeling, and immune response regulation via plant microRNAs and metabolites
PDELNs demonstrate excellent safety profile with zero reported toxicity, making them viable for clinical translation