Epitranscriptomic modulations optimize crop traits via messenger RNA modifications.
Ren Y, Li D, Gregory BD, Li F, Raynaldo FA
Summary
PubMedResearchers are studying how chemical modifications to messenger RNA can improve crop traits like yield, quality, and stress resilience—a reversible approach that offers new precision breeding opportunities. Analysis of 13 validated crop cases across cereals, fibers, and vegetables shows how these molecular switches control yield and resilience traits.
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Key Findings
13 functionally validated crop cases documented across cereals, fiber crops, and horticultural species with epitranscriptomic modifications
Epitranscriptomic enzymes and readers directly connect to yield components, quality traits, and stress resilience in crops
Dynamic mRNA modifications provide a reversible post-transcriptional regulatory layer for fine-tuning trait-related gene expression
Original Abstract
Rising global demand for food quantity and quality requires precision strategies on fine-tuning trait-related gene expression targeting crop improvement. Dynamic covalent modifications on mRNA add a reversible layer of post-transcriptional regulation on gene expression, yet their trait-level logic in crops remains fragmented. Recent studies connect epitranscriptomic enzymes and readers to yield components, quality traits and stress resilience. Here, we summarize regulatory mechanisms of covalent modifications emerging from 13 functionally validated crop cases across cereals, fiber and horticultural species, focusing on how m
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