CRISPR Base Editing Creates Herbicide-Tolerant Rice Without Transgene Integration
Shimatani Z, Kashojiya S, Nishida K
Summary
PubMedBase editing creates herbicide-resistant rice that's molecularly identical to natural mutations, potentially bypassing GMO regulations.
chevron_right Technical Details
Key Findings
No foreign DNA integration
Identical to natural ALS mutants
Potential non-GMO regulatory status
Original Abstract
Cytosine base editing of acetolactate synthase (ALS) in rice produced herbicide tolerance without any foreign DNA integration. Edited lines were indistinguishable from natural ALS mutants at the molecular level. Regulatory implications: base-edited crops may qualify as non-GMO in several jurisdictions.
This connects to 10 other discoveries — 1 species, 4 topics, 5 related articles
Species Mentioned
Rice is a cereal grain and in its domesticated form is the staple food of over half of the world's population, particularly in Asia and Africa. Rice is the seed of the grass species Oryza sativa —or, much less commonly, Oryza glaberrima. Asian rice was domesticated in China some 13,500 to 8,200 y...
open_in_new Wikipedia