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Plant Coumarins Modulate Natural Product Biosynthesis in a

Diab E, Du C, Tigani W, Elsayed SS, van Wezel GP

Summary

PubMed

Plants release chemical compounds called coumarins that influence the microbial communities living around their roots, which in turn affects how those microbes produce beneficial natural products. This chemical communication between plants and their microbiome could open new doors for developing sustainable alternatives to conventional pesticides and fertilizers.

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Key Findings

1

Plant-produced coumarins act as signaling molecules that modulate natural product biosynthesis in root-associated microorganisms

2

The plant microbiome plays a measurable role in regulating plant health and resilience, supporting its potential as a target for eco-friendly agrochemical alternatives

3

Coumarin-microbiome interactions represent a mechanism by which plants actively shape the functional output of their surrounding microbial communities

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Original Abstract

The plant microbiome plays a central role in regulating plant health and resilience, providing eco-friendly alternatives to agrochemicals. Plant-associated

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