Unveiling the Potential of Plant-derived Exosomes: A Comprehensive Review.
Jaiswal S, Sethi M, Rana R, Tripathi S, Trivedi AK
Summary
PubMedPlant-derived exosomes are tiny particles naturally produced by plants that could revolutionize drug delivery and cancer treatment, offering safer alternatives to human-derived exosomes. They show promising anti-cancer and antioxidant properties with high medication delivery efficiency, though researchers need to refine extraction and purification methods.
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Key Findings
Plant-derived exosomes overcome technical limitations of mammalian exosomes and function as effective nanocarriers for diverse medications
PDEs demonstrate anticancer and antioxidant therapeutic properties with high reproducibility in drug loading and delivery
Current isolation and purification techniques for PDEs remain time-consuming, technically challenging, and sometimes present safety risks
Abstract Preview
Extracellular vesicles, including exosomes, are naturally produced by various cell types both in vivo and in vitro. These nanovesicles, composed of a lipid bilayer, proteins, and RNAs, play a pivot...
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