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base-editing

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Base-editing is a precision genome editing technique that catalyzes the direct conversion of individual DNA bases without creating breaks in the DNA helix, enabling more accurate edits than conventional CRISPR systems. In plant science, base-editing facilitates the development of crops with improved traits—such as enhanced disease resistance, environmental stress tolerance, and yield—through targeted modifications that minimize unintended genetic changes.

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CRISPR Base Editing Creates Herbicide-Tolerant Rice Without Transgene Integration

PubMed · 2026-02-27

Base editing creates herbicide-resistant rice that's molecularly identical to natural mutations, potentially bypassing GMO regulations.

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No foreign DNA integration

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Identical to natural ALS mutants

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Potential non-GMO regulatory status

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