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anti-inflammatory-compounds

1 article

Anti-inflammatory compounds are bioactive secondary metabolites synthesized by plants that inhibit inflammatory pathways and responses. These compounds are significant to plant science because they reflect the plant's own chemical defense strategies against pathogens and environmental stress. Understanding their biosynthesis and regulation provides insights into plant physiology while enabling the discovery of therapeutically valuable plant-derived medicines.

Targeted alleviation of local inflammation by a hydroxypropyl-cyclodextrin-encapsulated prodrug of methyl salicylate and menthol though Nrf2/NF-κB pathway.

PubMed · 2026-02-15

Researchers developed a new treatment combining two plant-derived compounds—methyl salicylate and menthol—to treat inflammation and pain while avoiding antibiotic side effects. The innovation uses an advanced delivery system that releases the active ingredients precisely where inflammation occurs, improving effectiveness while reducing harm to the rest of the body.

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The formulation effectively reduced inflammation in pharyngitis and paw edema models with no observed systemic toxicity

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Targeted drug delivery system released active compounds in response to inflammation, enhancing local effectiveness while reducing systemic exposure

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Synergistic anti-inflammatory effects achieved by simultaneously inhibiting NF-κB pathway and activating Nrf2 pathway